Fluconazole (Diflucan)

Category:

  • Antifungal

Description:

  • Antifungal

Indications:

  • Candidiasis therapy and prophylaxis

  • Crytococcal menigitis

  • Vaginal Candidiasis

Contraindications:

  • Known sensitivity to fluconazole 

Precautions:

  • Pregnancy category C

  • Culture specimens to determine causative organism, use emperically then continue or alter therapy as indicated.

Adverse Reactions (Side Effects):

  • Headache (13%)

  • Nausea (7%)

  • Abdominal pain (6%)

  • Diarrhea (3%)

Dosage:

Administered orally and as injectable

Adult

Vaginal Candidiasis: 

  • 150mg for one time dose

Oropharyngeal and Esophageal Candidiasis: 

  • 200mg on day 1, then followed by 100mg daily for 14 days

Other Candidiasis: 

  • Doses up to 400mg per day until cured

Crytpococcal Meningitis: 

  • 400mg on day 1, then followed by 200mg daily for ten to twelve weeks following culture-negative cerebral spinal fluid

Child:

  • 3 mg/kg for adult dose of 100mg

  • 6 mg/kg for adult dose of 200mg

  • 12 mg/kg for adult dose of 400mg

The information contained here is an abbreviated summary. For more detailed and complete information, consult the manufacturer's product information sheets or standard textbooksSource:

Operational Medicine 2001,  Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300  

Gynecology and Obstetrics CD-ROM
Volumes 1-6
2004 Edition
 Lippincott Williams & Wilkins
Copyright 2004
All Rights Reserved