Fluoride Sodium (Luride, Pediaflor, Pharmaflur, Gel-Kam, various)

Category:

Miscellaneous

Description:

Anti-dental caries agent

Indications:

Prevention of dental caries

Contraindications:

Hypersensitivity

Precautions:

Pregnancy and lactation: Administration from 3^rd-9^th month of gestation safe (no information on teratogenicity); small amounts excreted into breast milk, inadequate therapeutically due to small amount of excretion and complexation with calcium
Drinking water >0.7 ppm fluoride

Adverse Reactions (Side Effects):

EENT: watery eyes
GI: black tarry stools, constipation, diarrhea, discoloration of teeth, hematemesis, increased salivation, loss of appetite, nausea, stomatitis, weight loss
METAB: hypocalcemia
MS: articular and juxta-articular pain, osteomalacia, stress fractures, tetany
RESP: decreased respiration, respiratory arrest

Dosage:

Administered orally (drops, lozenges, tablets, rinse, gel)

NOTE: 2.2mg sodium fluoride equivalent to 1mg fluoride ion

Adult and child >12 years:
- Dental rinse: TOP apply 10ml 0.2% solution every day after brushing teeth, rinse mouth for >1 minute with solution then expectorate
Child:
- Brush-on-gel: After brushing with toothpaste, >6 years apply thin ribbon of gel to teeth with toothbrush for at least 1 minute at bedtime, expectorate gel and rinse mouth thoroughly
- Dental rinse: TOP 5ml 0.2% solution daily after brushing teeth, rinse mouth for >1 minute with solution then expectorate
- Gel drops: >6 years: use applicators supplied by dentist; apply 4-8 drops to inner surface of applicator, spread evenly with tip of bottle; place applicator over upper and lower teeth and bite down gently for 6 minutes; remove and rinse mouth
Systemic protection from periodontal disease: PO in areas where fluoride content of drinking water < 0.3 ppm, <2years 0.25mg fluoride daily, 2-3 years 0.5mg daily, 3-12 years 1mg daily; in areas where fluoride content of drinking water is 0.3-0.7 ppm, <2 years 0.125mg fluoride daily, 2-3 years 0.25mg daily, 3-14 years 0.25-0.75mg daily

Source: Operational Medicine 2001, Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300