Methadone

Methadone (Dolophine)

Category:

Analgesic

Description:

Synthetic opiate agonist analgesic

Indications:

Severe pain
Heroin and Opiate detoxification

Contraindications:

Patients with impaired respiratory function.

Precautions:

Pregnancy Category C
May induce pulmonary edema
Rapid administration may induce respiratory depression, therefore monitor patient’s respiratory function.
Patients will experience CNS effects of drowsiness and dizziness, therefore use caution with motor vehicle operation or other hazardous tasks.
Use with caution with other CNS depressive medications.
Like any narcotic, may be addictive when used for prolonged periods of time (weeks to months).

Adverse Reactions (Side Effects):

Sedation
Dizziness
Constipation
Excessive sweating

Dosage:

Administered orally, SQ, or IM

Pain relief:

Normal oral, SQ or IM: 2.5-10mg q3-4h as needed

Detoxification:

Packaged as a dispersible tablet.
Diluted in oral liquid to decrease potential for IV abuse

The information contained here is an abbreviated summary. For more detailed and complete information, consult the manufacturer's product information sheets or standard textbooks.

Source: Operational Medicine 2001, Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300