Paroxetine (Paxil)

Category:

• Antidepressant

Description:

• SSRI (Selective serotonin uptake inhibitor)

Indications:

• Depression

• Obsessive-compulsive disorder

• Panic disorder

Contraindications:

• Concurrent use of MAO inhibitors

• Concurrent use of other SSRIs

Precautions:

• Pregnancy Category C

Adverse Reactions (Side Effects):

• Insomnia

• Decreased libido

• Ejaculatory failure

• Nausea

• Fatigue

• Dry mouth

• Dizziness

• Nausea

Dosage:

Administered orally (tablets)

Adult:

• Depression: 20 mg PO QD

• Obsessive-compulsive disorder: 

  • 20 mg PO QD x 1 week, then 

  • 30 mg PO QD x 1 week, then 

  • 40 mg PO QD

• Panic disorder: 

  • 10 mg PO QD x 1 week, then 

  • 20 mg PO QD x 1 week, then

  • 30 mg PO QD x 1 week, then

  • 40 mg PO QD

Therapeutic effects may not appear for a week or longer after initiating therapy. Changes in dosage should not be made more often than weekly.

Gynecology and Obstetrics CD-ROM
Volumes 1-6
2004 Edition

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